| Table 2. Embryological and clinical outcome parameters for each group. | |||||
| Parameters | Group 1 | Group 2 | Group 3 | Group 4 | p-value |
| P4i ≤ 1.5 and P4 f ≤ 1.5 |
P4i ≤ 1.5 and P4 f > 1.5 |
P4i > 1.5 and P4f ≤ 1.5 |
P4i > 1.5 and P4 f > 1.5 |
||
| 350 | 51 | 11 | 6 | ||
| Nº Cycles | 393 | 51 | 11 | 6 | |
| Oocytes retrieved | 7.62 ± 4.71ab | 11.47 ± 5.91a | 7.54 ± 5.42c | 18.16 ± 10.36bc | abc< 0.05 |
| MII oocytes retrieved | 4.85 ± 3.45a | 7.52 ± 4.73ab | 3.90 ± 3.80b | 10.33 ± 7.33 | ab< 0.05 |
| Maturation rate (M2/oocytes retrieved) | 63% (1905/2997)a | 65% (384/585)b | 52% (43/83)ab | 57% (62/103)ab | ab< 0.03 |
| Fertilization rate | 80% | 77% | 72% | 71% | NS |
| Embryos cleavage rate | 99% | 99% | 99% | 98% | NS |
| Nº embryos transferred | 2.14 ± 0.73 | 2.60 ± 0.77 | 2.09 ± 0.83 | 2.50 ± 0.83 | NS |
| Embryos ≥ 8CG1/G2 transf | 1.27 ± 0.92a | 1.72 ± 0.96abc | 0.81 ± 0.96c | 1.16 ± 0.98b | abc< 0.05 |
| Biochemical pregnancy | 40.71% (160/393)a | 33.33% (17/51)b | 27.27 (3/11) | 16.66% (1/6)ab | ab< 0.05 |
| Clinical pregnancy/cycle | 38.67 (152/393)a | 33.33% (17/51)b | 27.27% (3/11) | 16.66% (1/6)ab | ab< 0.05 |
| Implantation rate | 23.48% (198/843)abc | 14.28 % (19/133)ad | 13.04% (3/23)ce | 6.66% (1/15)bde | acde< 0.05b< 0.01 |
| Singletons | 71.05% (108/152) | 88.23% (15/17) | 100% | 100% | |
| Twins | 27.62% (42/152) | 11.46% (2/17) | 0 | 0 | |
| Triplets | 1.13% (2/162) | 0 | 0 | 0 | |
| Ectopic pregnancy | 0.65% (1/152) | 0 | 0 | 0 | |
| Abortion | 11.84% (18/152)ab | 47.05% (8/17)a | 33.33% (1/3)b | 0 | ab< 0.05 |
| Life Birth rate/cycle | 33.84% (133/393)abc | 17.64% (9/51)a | 18.18% (2/11)c | 16.66% (1/6)b | abc< 0.05 |
| Stillbirth | 1.13% (2/152) | 0 | 0 | 0 | |