| Table 1. Pregnancy results. |
| Author, year |
Country |
Number children malformation (ICSI) |
Number children malformation (Control) |
Type of Malformation |
OR |
95% CI |
Weight |
| Hansen et al., 2002 |
Australia |
18 (9.7%) |
164 (4.2%) |
Major |
3.629 |
1.778-7.406 |
0.76 |
| Farhangniya et al., 2013 |
Iran |
17 (6.5%) |
29 (4.4%) |
Major |
1.525 |
0.792-2.935 |
0.91 |
| Bonduelle et al., 2005 |
5 European countries |
178 (33%) |
117 (22%) |
Both |
1.757 |
1.345-2.297 |
5.43 |
| Sanchez-Albisua et al., 2007 |
Germany |
16 (47%) |
8 (20.5%) |
Both |
3.275 |
1.239-8.660 |
0.41 |
| Halliday et al., 2010 |
Australia |
235 (6.5%) |
1003 (4.8%) |
Major |
1.411 |
1.201-1.657 |
15.06 |
| Davies et al., 2012 |
Australia |
182 (9.7%) |
16989 (5.4%) |
Major |
2.276 |
1.864-2.778 |
9.78 |
| Källén et al., 2005 |
Sweden |
307 (5.8%) |
80881 (3.4%) |
Major |
1.636 |
1.424-1.879 |
20.2 |
| Belva et al., 2007 |
Belgium |
15 (10%) |
5 (3.4%) |
Both |
2.849 |
1.151-7.052 |
0.47 |
| Fedder et al., 2013 |
Denmark |
488 (7.9%) |
1952 (3.0%) |
Major |
4.252 |
3.687-4.904 |
19.14 |
| Sutcliffe et al., 2003 |
Australia and UK |
15 (5.7%) |
15 (5.8%) |
Minor |
0.984 |
0.471-2.055 |
0.72 |
| Sutcliffe et al., 2001 |
UK |
32 (15.3%) |
24 (10.8%) |
Both |
1.488 |
0.849-2.609 |
1.24 |
| Ombelet et al., 2005 |
Belgium |
36 (2.2%) |
70 (2.1%) |
Major |
1.019 |
0.678-1.532 |
2.34 |
| Place & Englert, 2003 |
Belgium |
7 (10.6%) |
8 (13.5%) |
Both |
0.758 |
0.258-2.223 |
0.34 |
| Hansen et al., 2012 |
Australia |
53 (9.0%) |
11078 (5.4%) |
Major |
2.047 |
1.430-2.930 |
3.02 |
| Klemetti et al., 2005 |
Finland |
40 (4.6%) |
756 (2.8%) |
Major |
1.885 |
1.259-2.823 |
2.39 |
| Farhi et al., 2013 |
Israel |
67 (2.5%) |
3700 (1.8 |
Major |
1.483 |
1.114-1.974 |
4.76 |
| Funke et al., 2010 |
Hungary |
13 (2.3%) |
155 (1.1%) |
Major |
3.055 |
1.372-6.800 |
0.61 |
| Bonduelle et al., 2004 |
Belgium, Sweden and USA |
19 (6.3%) |
8 (3.0%) |
Major |
2.077 |
0.958-4.502 |
0.65 |
| Katalinic et al., 2004 |
Germany |
183 (8.9%) |
472 (6.0%) |
Major |
1.600 |
1.316-1.946 |
10.18 |
| Knoester et al., 2007 |
The Netherlands |
6 (6.9%) |
5 (5.9%) |
Both |
1.183 |
0.350-4.001 |
0.26 |
| Total |
|
|
|
|
1.987 |
1.867-2.115 |
100% |