ISSN 1518 0557
Serum estradiol level on the day of trigger as a predictor of number of metaphase II oocytes from IVF antagonist cycles and subsequent impact on pregnancy rates

2021; 25
Héctor Salvador Godoy Morales, Miguel Loyo Guiot, , Germán Gabriel Palacios López, Daniel Vieyra Córtes, Berenice Flores Maldonado, Hilda Sánchez Hernández, Griselda Claribel Reyes Torres, Francisco Miguel Rojas Camacho, Gabriela Ayala Montoya
JBRA Assist. Reprod. 2021; 25 (3):447-452

Received August 08, 2020
Accepted February 20, 2021
Abstract

Objective: To determine the association of serum estradiol levels with the number of metaphase II oocytes collected via in vitro fertilization cycles and embryo transfer to predict the pregnancy rate. Methods: Observational, analytical, retrospective study conducted during 2010-2018 at Angeles del Pedregal Hospital, where 181 clinical cases were reviewed, focusing on the number of metaphase II oocytes to predict pregnancy rate. Statistical analysis was based on the calculation of variables correlation and logistic regression. Results: It was found that estradiol levels increase with the number of oocytes with a median correlation (r 0.482, p 0.000). On the day of trigger, estradiol levels predict with 23% reliability the number of retrieved oocytes, (R2 0.232, p 0.000), as well as a linear tendency correlation of r 0.489, p 0.000 between the estradiol levels on the day of trigger and the number of metaphase II oocytes. Conclusions: Serum estradiol on the day of trigger as a prediction of metaphase II oocytes in cycles with antagonists encourages greater oocyte maturity and fertilization, whereas, in isolation, it does not determine the pregnancy achievement.


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doi: 10.5935/1518-0557.20210007

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