Received February 06, 2021
Accepted July 31, 2021

The aim of this study was the effect of nanoalumina on sex hormones, and fetus in pregnant rats. In this study, Sixty four pregnant rats were divided to eight groups. Control and injection control group received normal food and water and 0.5 ml of distilled water, respectively. Treatment groups were treated with 25, 50, 100, 250, 500, and 1000 μg/ml concentrations of Nanoalumina from the 7th day until the 18th day of pregnancy. On the 18th day, rats were investigated in terms of their hormone levels. The number of healthy and aborted as well as size of fetus was also evaluated. Nanoalumina led to an increase in progesterone hormones at the concentrations of 250, and 500μg/ml, and a significant reduction in estrogen hormone and aborted fetuses at the concentrations of 250 and 500 μg/ml (p <0.05). The largest and smallest size of fetus was observed in 500 μg/ml and 1000 μg/ml, respectively. The highest number of aborted fetuses was observed in the group treated at 500 μg/ml concentration. There is no aborted fetus neither in 25, 50,100, control, and injection control groups. Du to toxicity of nanoalumina , it must be used by more caution.