Received May 10, 2021
Accepted October 20, 2021

Objectives: Infertility, defined as the inability to conceive after one year of intercourse without the use of contraception, affects 15% of couples. Many factors, such as genitourinary tract infections, endocrine disorders, immunological factors, and drug-related injuries, affect the male reproductive system and lead to infertility. Due to men's fear of infertility, it is very important to pay attention to medicinal plants that are effective in male fertility. Therefore, the aim of this study was to evaluate the medicinal plants that affect sperm production and testosterone in men. Methods: In this review study, the search terms consisting of herbal medicine, traditional medicine, traditional therapies, sperm, testosterone, testicles and Iran were used to retrieve the relevant articles published in the journals indexed in Information Sciences Institute, Science Direct, PubMed, Scopus, PubMed Central and Scientific Information Databases. Published papers in 2000-2020 were searched and were used for reviewing. Then, the findings of eligible articles were analyzed. A total of 35 articles were collected from databases, and retrieved articles from databases were analyzed. Only the articles about herbs that affect sperm production and testosterone hormone were selected for the study. Results: Based on the results, herbs Apium graveolens, Cinnamomum camphora, Cornus mas, Satureja khuzestanica, Withania somnifera, Fumaria parviflora, zingiber officinale, cinnamomum zeylanicum and Phoenix dactylifera are used for male reproductive system. Conclusion: Plants can probably be useful in increasing fertility due to their antioxidant power and less side effects.