Fernando Zegers-Hochschild, Javier Crosby, Carolina Musri, Maria do Carmo Borges de Souza, A. Gustavo Martínez, Adelino Amaral Silva, José María Mojarra, Natalia Posada, Diego Masoli, on behalf of the Latin American Network of Assisted Reproduction
JBRA Assist. Reprod. 2021; 25 (4):617-639
Received July 01, 2021
Accepted September 03, 2021
Abstract
Research question:What are the trends in patient characteristics, effectiveness, and safety of ART performed in Latin America for the past three decades; and detailed outcome of procedures initiated in 2018.
Design:Retrospective collection of multinational data including epidemiologic and outcome of ART performed between 1990 and 2018.
Results: In these 30 years we report 955,117 initiated cycles, 191,191 deliveries and 238,045 livebirths. In 1990, 66.5% of women were ≤34 years and 8.7% ≥40; while in 2018, 27.8% of women are ≤34 and 30.5%, ≥40 years. In 1990, 60.4% of transfers included ≥3 embryos, dropping to 13.5% in 2018, and SET increased from 13.8% to 30.4% between 1990 and 2018. Delivery rate per fresh transfer increased from approximately 17% in the nineties to 25% in 2018; with a meaningful drop of high order multiples from 8-9% in the nineties to 0.4% today. This drop is associated with increasing use of FET (57%) compared with 10% in 2000. Furthermore, today, delivery rate in FET is 28.3% reaching 31.2% in freeze all cycles; and a cumulative live birth of 41.9%. Elective (e)SET also increased; from 0.9% in 2010 to 10% in 2018. The delivery rate in eSET (31.7%) is only 5.4% lower than eDET (37.1%); however, multiple births increases from 2.1% to 25% twins and 0.4% triplets in eDET.
Conclusion: RLA celebrates 30 years of voluntary reporting of now more than 200 centers in 15 countries. This South-South Cooperation network has proven to be an efficient and safe system for technologic transfer and regional growth.
