Silvana Márquez Hinojosa, Luis Noriega Hoces, Luis Guzmán
JBRA Assist. Reprod. 2022; 26 (3):432-443
Received April 03, 2021
Accepted November 29, 2021
Abstract
Conventional embryo assessment is performed by removing embryos from incubators at least once a day. However, it is static and limited to specific time points, reducing the amount of information that could potentially be obtained. Fortunately, time lapse system is a powerful technology that provides the possibility of observing the progression of embryo development by image acquisition at recurrent time intervals without interfering culture conditions.
A fascinate amount of studies that used time lapse incubators have been published, studies has focused on embryo kinetics, patient characteristics and clinical outcomes. This review aims to find agreements among literature for embryo kinetics and patients characteristics: age, body mass index, smoking habits, polycystic ovary syndrome and endometriosis as well as culture conditions that involved culture media and oxygen concentration. Furthermore, showed the differences according to ploidy status, direct/reverse cleavage, gender and the potential association between embryo collapse and clinical outcomes.