Received February 04, 2022
Accepted September 07, 2022

Objective: due to the large increase in number of reported cases and the impact of the COVID-19 coronavirus on public health, the European Society for Human Reproduction and Embryology (ESHRE) recommended the cessation of any activity related to assisted reproduction. There are many unknowns about the long-term effects of the virus on fertility and pregnancy, we conducted this study to offer some evidence-based guidance, to evaluate the relation of the covid-19 and the outcome of IVF/ICSI cycles. Methods: this is an observational study, for 179 cases who underwent ICSI which was conducted in Al- Baraka Fertility Hospital, Manama, Bahrain and Al-Manea hospital, KSA, and divided into 2 groups, group1 included 88 with history of confirmed covid-19 infection and group2 which included 91 cases without history of infection. Results: despite the higher pregnancy rate [45.1% vs 36.4%, with p=0.264] and fertilization [52% vs 50.6% with p=0.647] in covid-19 negative patients than previously infected patients, these differences were not clinically significant. Conclusion: Based on these data, there is no clear evidence that the previous exposure to Covid-19 virus infection can affect the outcome of ICSI cycles significantly.