More than two years into the SARS-CoV-2 pandemic, the effects of the virus on the male and female reproductive system remain controversial. On the one hand, men with active infection harbor the virus for a short period, from 2 to 11 days, symptoms eventually referred to reproduction organs can be simply attributed to hyperthermia and/or or hypoxia. Infections in remission showed the virus in the semen in 1.4% versus 6% of the cases evaluated in the active phase, not seeming to worsen the spermogram parameters. A single case described as a positive semen test at 21 days of recovery showed that the stable partner, under unprotected sex, tested negative with oropharyngeal, rectal and vaginal smears, indicating viral RNA and not a live virus active in the semen. In women, one can theoretically expect compromise of the ovary, uterus and vagina, as well as the endometrium and breasts, with menstrual disorders and secondary infertility, effects that have also not been clear to date.