ISSN 1518 0557
Fertility preservation: a case report of a newborn following 13 years of oocyte cryopreservation

2023; 27
Ricardo Azambuja, Mariangela Badalotti, Lilian Okada, Luciana Segurado Cortes, Marta Hentschke, Alvaro Petracco
JBRA Assist. Reprod. 2023; 27 (2):328-331

Received April 04, 2022
Accepted November 17, 2022
Abstract

Introduction: The oocyte cryopreservation allows the storage of genetic material, especially in situations where the ovarian function is compromised, and also for women desiring to postpone maternity. Before 2012 the oocyte cryopreservation was still experimental, and the success of the procedure was uncertain. However, was the possibility that women had for fertility preservation. Thus, we aim to report a case of a birth after 13 years of elective oocyte cryopreservation. Case Description: At 49 years old, a patient returned to our reproductive center with the desire to get pregnant, using their oocytes that had been frozen for 13 years. The endometrium was prepared, and the oocytes were thawed using the slow procedure method. Four of the six oocytes thawed survived (66%) and were inseminated; three fertilized and started their development. The transfer of two embryos on the third day of development was performed. Clinical pregnancy was confirmed via ultrasound and came to term with the birth of a healthy boy. Discussion: Although the vitrification procedure has shown to be a better cryopreservation technique when compared to slow freezing, the latter represented an important role when patients wanted to cryopreserve oocytes in early 2000. Even many years later, this technique reveals its efficacy, preserving the viability and quality of oocytes stored in nitrogen tanks. After literature review, this case seems to be the largest interval between oocyte cryopreservation and its use, with achieved pregnancy, in Brazil.


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doi: 10.5935/1518-0557.20220070

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