This edition of JBRA presents part of the twenty first edition of the Latin American Registry of Assisted Reproductive Technology (RLA). One hundred and forty centers from thirteen countries reported data involving ART procedures performed from January to December 2010. These data also represent the first multinational registry of published in a case-by-case report by RLA. Last year we began this tradition of presenting the main data in the official journal of REDLARA. It was a wise decision that brings all the centers to be aware of the strength of RLA, and the possibilities to research we have. At the same time, it enables others groups that still are not within RED to understand the importance in joining this Registry. Reports from 1990 through 1998 are available as printed copies; from 1999 through 2009 are available as PDF files to be downloaded from the web page of Red Latino Americana de Reproducción Asistida (REDLARA) at www.redlara.com. As always, data from 2011 will also be there and with a free-access. We wish a Happy 2013 to all in LA, May the New Year come with Justice, Peace, Health , Friendship and Love to all of us.