Received August 02, 2022
Accepted February 21, 2023

Objectives: Primary: To evaluate the effect of low doses of recombinant hCG (choriogonadotropin alfa) in the luteal phase of frozen-thawed embryo transfer (FET) of artificial cycles on the chances of pregnancy in patients aged ≤ 38 years. Secondary: Assess the chances of pregnancy in the FET groups of artificial cycles using micronized vaginal progesterone (VP) versus injectable intramuscular progesterone (IMP) and the chances of pregnancy in type 1 embryo transfers (two top embryos). Methods: This retrospective cohort study included 122 cicles of FET that compares two groups that use or not hCG in luteal phase, in patients aged ≤ 38 years. Results: The clinical pregnancy rates (CPR) in the control group use and in the hCG group were 45% and 45.16%, respectively (p=0.9999). The live birth rate (LBR) was 33.33% and 32.25%, respectively, (p=0.99909). The CPR in the VP group (83 patients) were 46.89% versus 41.02% in the IMP group, (p=0.5459). LBR was, respectively, in VP group 33.73% versus 30.76% in IMP group (39 patients), (p=0.7559). Conclusions: The CPR, LBR of FET indices in the groups using low doses of recombinant hCG and without use of it were similar. The groups that used VP and IMP also showed no significant difference.