María Noelia Poli, Lucía Amalia López Miranda, Eduardo Daniel Gil, Germán Zanier, Pedro Fernández Iriarte, Justo Hector Mario Zanier, Roberto Coco
JBRA Assist. Reprod. 2016; 20 (2):62-65
Received July 15, 2015
Accepted January 19, 2016
Abstract
Objective: This paper aimed to estimate the frequency of occurrence and the types of chromosomal abnormalities found in 141 infertile men with abnormal sêmen parameters.
Methods: the frequency and type of chromosomal abnormalities were determined with male mitotic karyotype analysis from peripheral blood through chromosome banding techniques before assisted reproduction procedures. Results: In this series of 141 infertile men, 19 (13%) had chromosomal anomalies and 35 (25%) had polymorphic variants. The main chromosome abnormalities were reciprocal translocations and marker chromosomes in mosaic. Conclusions: These results stress the relevance of cytogenetic studies for infertile males as a diagnostic tool and a valuable input in genetic counseling.
