Claudia Gomes, Mariana Nicolielo Barreto, Anaíde Silva Sousa, Dayane Reis, Priscila Beirigo, Izadora Reis, Caroline Fauth, Andrea Belo, Hanna Park, Ana Luiza Tavares, Livia Munhoz, José Roberto Alegretti, Dóris Chéles, Aline Rodrigues Lorenzon
JBRA Assist. Reprod. 2025; 29 (1):191-194
Received March 29, 2024
Accepted September 30, 2024
Abstract
Natural conception in women after the age of 45 years is rare. The probability of successful pregnancy in this specific group of women after IVF and embryo transfer with autologous oocytes is also reduced. In addition, advanced maternal age is associated with an increased risk of aneuploidies and other associated complications during pregnancy. Generally, women who are over 44 years old are advised to receive IVF treatment with donated oocytes due to poor oocyte quality and low ovarian reserve. Although IVF outcomes in women of advanced age can be associated with the best prognosis when donated oocytes are used, IVF is not always well accepted by infertile couples. This is a case report of a woman who achieved a clinical pregnancy and live birth in her first attempt at IVF treatment with her own eggs and a euploid embryo at 48 years and 10 months, respectively, at the time of oocyte retrieval. This case demonstrates that limited attempts at assisted reproductive technology with older women�s own eggs may be an option in specific cases.
