Daniela Braga, Amanda Setti, Patricia Guilherme, Assumpto Iaconelli Junior, Edson Borges Jr.
JBRA Assist. Reprod. 2025; 29 (3):430-436
Received September 27, 2024
Accepted September 01, 2025
Abstract
OBJECTIVE: This study explores the influence of seasonal variations on embryo morphokinetics and the outcomes of intracytoplasmic sperm injection (ICSI) cycles. METHODS: This retrospective cohort study, performed in a private university-affiliated IVF center from March 2019 - March 2023, included 1,292 intracytoplasmic sperm injection cycles (ICSI) cycles and 8,376 injected oocytes. Cycles and were split depending on the season in which oocyte collection was performed: Spring (n=462 cycles), Summer (n=176 cycles), Autumn (n=258 cycles), and Winter (n=396 cycles). Embryos were cultured in a time-lapse imaging (TLI) incubation system, and embryo morphokinetics and laboratory and clinical outcomes were compared between the groups. RESULTS: A slower morphokinetic development was observed in embryos derived from cycles performed in the winter compared to those from cycles performed in other seasons, while embryos derived from cycles performed in the summer exhibited faster embryo development. Significantly longer
