Eliana Margarita Retamoso-Paz, Marisol Martinez-Martinez, Luz Sthefany Chavarro-Tello, Clara Ines Esteban-Perez
JBRA Assist. Reprod. 2026; 30 (1):225-228
Received May 16, 2025
Accepted February 20, 2026
Abstract
This case report aimed to describe a case of healthy live birth after in vitro fertilization (IVF) resulting from the transfer of a euploid embryo derived from tri-pronuclear zygote (3PN). We also made a review of the literature on this subject. The case was set in a private practice IVF center. A nulliparous 29-year-old woman with abnormal ovarian reserve test, and male factor infertility who underwent IVF. Embryonic preimplantation genetic test for aneuploidy and confirmation of a normal ploidy constitution was correlated with prenatal noninvasive cell-free fetal DNA test. In this case report, we provide evidence that a transfer of a euploid embryo derived from an abnormally fertilized oocyte (tri-pronuclear zygote) can result in a clinical pregnancy and healthy live birth.
