ISSN 1518 0557
Toward clarity: why we need to standardize the term ‘recurrent pregnancy loss´

2025; 29
Luiza Pretto, Eduarda Nabinger, Ivan Sereno Montenegro, Maria Teresa Vieira Sanseverino, Osvaldo Artigalas, Fernanda Sales Luiz Vianna, Eduardo Pandolfi Passos, Lucas Rosa Fraga
JBRA Assist. Reprod. 2025; 29 (3):407-410

Abstract

Recurrent pregnancy loss (RPL) is a complex reproductive condition that remains difficult to manage. Despite advances in identifying risk factors and treating cases with known etiologies, approximately half of the cases remain idiopathic, posing significant challenges to effective treatment and prognostic assessment. Beyond clinical complexities, a critical issue persists in both the literature and medical societies: the lack of standardization regarding the appropriate terminology and precise definition for RPL. Here we discuss the main discrepancies in current definitions and advocates for the adoption of the term ‘recurrent pregnancy loss’ as the most suitable and inclusive. We propose RPL being recognized as a specific subtype of secondary infertility, characterized by the occurrence of two or more pregnancy losses. Standardizing this terminology is essential for improving diagnosis, research comparability, and patient care in the reproductive medicine area.


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doi: 10.5935/1518-0557.20250158

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