ISSN 1518 0557
Early serum progesterone and prolactin analysis at day 9 of oocyte retrieval as a predictor of success in fresh ICSI cycles

2018; 22
Paulina Alejandra Santander Perez, Alvaro Pigatto Ceschin, Daniela Maria P de Moraes, Lucileine Keico S N de Oliveira, Ianae I Ceschin, Nathan I Ceschin
JBRA Assist. Reprod. 2018; 22 (2):95-98

Received February 22, 2017
Accepted October 18, 2017
Abstract

Objective: To analyze progesterone and prolactin plasma levels nine days after oocyte retrieval and evaluate their correlation with pregnancy rates in in vitro fertilization cycles. To achieve pregnancy, several factors are analyzed before and during the in vitro fertilization cycle. Progesterone supplementation for adequate luteal phase support is indicated despite the presence of multiple corpus luteum in IVF stimulation cycles because of blockage caused by hypothalamic agonists and antagonists. The dosage of progesterone and prolactin on day 09 after the follicular retrieval could function as a predictive marker of success in fertility treatments. Methods: A retrospective study was performed using data from 238 patients submitted to intracytoplasmic sperm injection (ICSI) at a private infertility clinic from January 2013 to December 2015. Hormonal measurements were performed on day 09 after follicular uptaken. The data was compared to assess the correlation between prolactin and progesterone dosages and pregnancy rates. Results: The ICSI pregnancy rate was 40.8% (n=238). No statistically significant difference was observed when correlating the success of the procedure with the prolactin dosage (p=0.71). However, progesterone showed a significant difference (p = 0.021). The cut-off point indicated by the ROC curve fit according to which gestations would be identified is 25.95 ng / ml progesterone. The sensitivity of this point is 61.9% and the specificity is 57.4%. Conclusion: Progesterone dosage may be one of the indicators of gestation on day 09 after follicular uptake. Such data can help physicians to monitoring and provides suitable early gestational care. More studies are needed to corroborate the data found.


This Article

doi: 10.5935/1518-0557.20180008

Full Text (HTML)
Full Text (PDF)

Classifications

Original article

How to cite

How to cite this article

Send this article

Send this article by mail

Access statistics

Last 30 days: 38
All time: 1861


Home

 
Copyright 2026 - JBRA Assisted Reproduction - All rights reserved.
Support and Maintenance by Eniosoft