Received November 28, 2017
Accepted July 14, 2018

The effect of acupuncture on IVF outcomes is still unknown. We conducted a systematic review and meta-analysis of RCT to determine whether acupuncture performed at the time of ET improves the outcome. We searched Medline and Embase from January 1990 to June 2017, for the following terms): (acupuncture; acupuncture therapy) and (reproductive techniques, assisted; fertilization in vitro; embryo transfer). We selected RCT that compared acupuncture with sham acupuncture or no treatment. . We included only trials in which acupuncture involved the insertion of needles into traditional meridian points. We evaluated the methodological quality of the trials using the Cochrane risk of bias tool. The measure of treatment effect was the pooled odds ratio of achieving a clinical pregnancy, ongoing pregnancy, or live birth for women in the acupuncture group compared with women in the control group. For pooled data, summary test statistics were calculated using the Mantel-Haenszel method, using Rev-Man software, version 5.1. We analyzed six studies, incluyen a total of 2,376. In all trials, there were no significant differences between the groups in the mean numbers of embryos transferred, mean age of the women undergoing the procedure, diagnose and use of ICSI. Acupuncture performed the day of ET was associated with a reduced risk ratio for clinical pregnancy (0.87, 95% confidence interval 0.77 to 0.98), (fig 2). The pooled rate difference was -0.06 (-0.12 to -0.01) for clinical pregnancy. None of the trials reported significant adverse effects of acupuncture.