ISSN 1518 0557
Higher follicular fluid glycodelin levels are negatively correlated with embryonic development in assisted reproduction

2018; 22
Sibel Bulgurcuoglu Kuran, Bilge Ozsait Selcuk, Funda Gungor Ugurlucan, Gozde Koksal, Can Gunay, Faruk Buyru
JBRA Assist. Reprod. 2018; 22 (4):346-351

Received December 30, 2017
Accepted August 07, 2018
Abstract

Objective: To investigate the possible e ect of follicular uid glycodelin levels on the quality of developing oocytes and subsequent in vitro embryo development. Methods: Follicular uid glycodelin levels of 145 patients undergoing assisted reproductive treatment were analyzed and the correlation between glycodelin levels and ART outcomes were evaluated. Results: We found that glycodelin levels were negatively correlated with the number of high quality embryos on day 3 (r=-0.20, p=0.05). Additionally, higher glycodelin levels were correlated with higher FSH levels (r=0.18, p=0.04). However, glycodelin levels were not predictive for implantation (p=0.67) or ongoing pregnancy rates (p=0.99). Conclusion: Glycodelin in the follicular environment might be one of the factors that in uence the competence of growing oocytes and a ect the quality of subsequent in vitro embryo development.


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doi: 10.5935/1518-0557.20180069

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