ISSN 1518 0557
Case report of Zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes

2019; 23
Edilberto Araújo Filho, Cássio Leão Fácio, Ligiane Alves Machado-Paula, Mariana Angelozzi de Oliveira, Ciro Dresch Martinhago, Leonardo Previato Araújo, Lígia Fernanda P. Araujo
JBRA Assist. Reprod. 2019; 23 (2):172-174

Received June 27, 2018
Accepted December 30, 2018
Abstract

We describe a case of a 37-year-old female, indicated for in vitro fertilisation. She developed skin rash on her trunk and limbs, during the treatment. RT-PCR results were positive in her blood and negative in her husband’s blood and semen. Oocyte aspiration was performed, retrieving 7 oocytes, follicular fluid, and cumulus cells. RT-PCR results for the follicular fluid and cumulus cells were negative for ZIKV, and positive for only 2 oocytes. This is the first report in the literature analysing ZIKV in the follicular fluid, cumulus cells, and oocytes, and will contribute to the understanding of ZIKV infection and transmission.


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doi: 10.5935/1518-0557.20180081

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