Luis Guzman, Naomi Inoue, Denisse Nuñez, Jazmin Meza, Pedro Bendezu, Pilar Pino, Jimmy Portella, Luis Noriega-Portella, Luis Noriega-Hoces
JBRA Assist. Reprod. 2019; 23 (2):106-111
Received June 05, 2018
Accepted December 31, 2018
Abstract
Objective: To describe our fertility preservation program focusing on the number of oocytes vitrified by age.
Methods: From January 2015 to December 2016; 686 oocyte vitrification cycles of social fertility preservation were performed in our units. In total, 288 were donors who donated her oocyte for our oocyte banking program and 398 were patients who underwent elective fertility preservation.
Results:
The mean numbers of COCs retrieved and vitrified oocytes were similar among the donor cycles (women under 30 years). On the contrary, in patients the mean numbers of COCs retrieved and vitrified oocytes significantly decline when patients were over 36 years.
We also estimated the association between age and cancelation rates. Odd ratios (OR) for total cancelation was calculated between patients of 31-35 years and 41-45 years; OR was 5.17 (95% CI 1.89 – 14.17) and increased up to 25.67 (95% CI 5.01 – 131.42) between 31-35 y and older than 45 years. No differences were found between patients of 31-35 years and 36-40 years. OR for total cancellation increased 3.83 (95% CI 2.06 – 7.11) and 19.00 (95% CI 4.56 – 79.11) between women 36-40 years and 41-45 years; older than 45 years respectively.
Finally, the oocyte survival rate in patients under 36 years was similar to our donor program (94% vs 95%).
Conclusions:
Based on this study, we encouraged our patients to preserve their fertility for the future.