Received November 16, 2013
Accepted November 16, 2013

OBJECTIVE: The aim of this study was to analyze the maternal and paternal contribution to aneuploidy present in blastocyst stage embryos in IVF/ICSI cycles, where it was done PGD for SNPs. METHODS: In order to do chromosome analysis, samples of trophoblast were obtained at day 5 or 6 of development, doing biopsy with a Lykos laser. Samples were sent to Genetic Solutions, for analysis using SNPs. RESULTS: We analyzed 46 cycles with 181 embryos. Of these, 24 were unsuccessful. Out of 157 embryos studied, 56.7% were euploid. By analyzing the rate of euploid embryos according to the age of the mother, it was found that the ratio falls when age increase. In women of 35 years or younger, 78% of embryos is normal and in women over 35years, the rate drops to 46.7%.When anomalies are separated from the mother and father and analyzed the effect of maternal age, we observed that the largest proportion of anomalies, comes from the oocyte and they increase with age. In women younger than 35years, 40% of aneuploidy is of maternal origin and this reaches 75% in women over 38 years. By analyzing the paternal contribution, no variations, with values below 10%, in the different age groups studied. CONCLUSION: It is suggested that the low implantation rates obtained in women older than 38years, would be related aneuploidies present in the oocyte.