Fernando Zegers-Hochschild, Juan Enrique Schwarze, Javier A. Crosby, Carolina Musri, Maria do Carmo Borges de Souza
JBRA Assist. Reprod. 2013; 17 (4):216-223
Received July 01, 2013
Accepted July 23, 2013
Abstract
Background:This 23rd report represents the results of ART procedures performed during 2011 by 145centers from 12countries in Latin America.
This is the second time the data was individually collected in a case-by-case modality.
Methods:All centers reported their ART procedures electronically and their data was accepted after consistency checks were performed and an accreditation team certified the institution. A total of 41,232 procedures included 28,065 initiated fresh homologous ART cycles consisting of 4,089 in vitro fertilization (IVF) cycles; 23,976 Intra cytoplasmic sperm injection (ICSI); 6,909 frozen embryo transfers(FET) and 6,258oocyte donations(OD), plus 14 cases of GIFT, which are not described in this report.
Results:Thirty eight percent of ET in IVF/ICSI cycles were performed in women age 35-39years, while 25% included in ICSI and IVF cycles were 20.7% and 23.9%, respectively.
The multiple delivery rate in IVF/ICSI cycles grouped together, was 22.3% (21.0% twins and 1.3% triples). When >/=2 embryos were transferred, neither the CPR nor the proportion of twins increased significantly. However, the proportion of triplet increased significantly when >/=3 embryos were transferred. In OD cycles, twin and triplet deliveries were 28.5% and 1.6%, respectively. In FET cycles, twin and triplet deliveries were 17.8% and 1.4%, respectively. Multiple deliveries were associated with a significant increase in preterm delivery and perinatal mortality. In cases of elective transfers, the DR was 19.8% with eSET and 35.8% with eDET.In women aged =34years, DR with eSET was 29.6% and 39.5% with eDET. Furthermore, in OD cycles, the DR with eSET was 25.0%, and 38.1% with eDET.
Conclusions: Overall, delivery rates are acceptable and comparable to most developed countries in the world. However, Latin American countries need to enforce the reduction in the number of embryos transferred in IVF/ICSI and OD cycles, in order to decrease the rate of multiple births and therefore decrease the corresponding perinatal complications.