Juliano Augusto Brum Scheffer, Rafaela Friche De Carvalho, Ana Paula de Souza Aguiar, Iole Joana Moreira Machado, Juliana Baumgratz Franca Franca, Daniel Mendez Lozano, Renato Fanchin
JBRA Assist. Reprod. 2021; 25 (1):109-114
Received March 03, 2020
Accepted September 04, 2020
Abstract
Objective: The aim of the present prospective study was to evaluate which ovarian reserve marker would be more reliable as the quality of the A + B embryos (day 3 and blastocyst).
Methods: 124 infertile women, aged 24-48 years, were studied prospectively, from 2017 to 2018. The patients were divided into 3 groups according to age and subgroups were compared for AMH, AFC, amount of embryos A + B . New division of the 3 groups was performed based on the AMH and subgroups were compared for age, AFC, amount of embryos A + B. Finally the patients were divided into 3 groups based on the AFC and the subgroups were compared for age, AMH, amount of embryos A + B. P <.05 was considered statistically significant.
Results: When the 124 patients were divided according to age, a significant fall in an embryo quality A + B (day3; blastocyst) after 35 years (p<0.038; p<0.035) and more severely after 37 years (p<0.032; p< 0.027). When the 124 patients were divided according to AMH, was observed the significant fall in embryo quality A + B (day3; blastocyst) with AMH<1 ng/ml (p<0.023; p<0.021). When the 124 patients were divided acoording to AFC, was observed a significant fall in embryo quality A + B (day3; blastocyst) with AFC< 7 (p<0.025; p<0.023). These markers had significant relationships with embryo quality (p<0,005)
Conclusion: Age, AFC and AMH have significant relationships with embryo quality A +B day 3 and blastocyst.