Received May 05, 2020
Accepted September 20, 2020

Objective: To identify the effects of interactive music therapy on stress level in women undergoing high complexity treatment for infertility. Material and Methods: Prospective randomized study conducted with 113 women treated in a Brazilian university clinical center, submitted to In Vitro Fertilization/ Intracytoplasmic sperm injection. Depression, Anxiety and Stress Scale and Lipp’s Stress Symptoms Inventory for Adults were used. In the Intervention Group, small, easy to play, percussive musical instruments, a guitar, voice, and a recorder were used. Interactive music therapy approach was used individually, applied before basal ultrasound, oocyte pick-up, and embryo transfer. Data were analyzed by the software R. Paired Student t test was used to compare the results. Results: Comparison of the stress levels by Depression, Anxiety and Stress Scale between the groups in the final moment of data retrieval resulted in 23.13 (SD±10.51; n = 32) in the Control Group and 16.12 (SD±7.87; n = 33) in the Intervention Group, being statistically different (p=0.004). Also in Lipp’s Stress Symptoms Inventory for Adults there was a significant stress reduction in 39% of the patients in the Intervention Group compared to a reduction of 14% in the patients of the Control Group (p=0.032). In this same measurement resulted that only 3% of the Intervention Group patients versus 23% of the Control Group patients (p = 0,027) were in exhaustion stage. Conclusion: Interactive music therapy was effective on stress reduction in women during assisted reproduction techniques.