Received June 30, 2020
Accepted January 04, 2021

Objective: The objective of this study was to evaluate the effects of overweight and obesity on fertility outcomes from in IVF procedures. Methods: A total of 191 IVF/ICSI cycles using non-donor oocytes performed between July 2016 and December 2018, were allocated according to Body Mass Index (BMI) in three groups: Normal group: 18.5-24.9 (n=67 women), Overweight group: 25.0-29.9 (n=86 women) and Obesity group: ≥30.0 (n=38 women). Fertilization rates, embryo quality at day 3, development and quality of blastocyst, pregnancy rate (PR), implantation rate (IR), and live birth rate (LBR) were compared. Results: Patients from all groups had similar stimulation days, but those women with overweight and obesity used more hormones compared to women with normal weight (P<0.05). Fertilization rate, zygotes that underwent cleavage, and good-quality embryos at Day 3 were similar between the three evaluated groups. The groups of overweight and obesity had embryos at Day 3 with significantly less cells compared to those from the normal group (P<0.05). The blastocyst development rate was significantly lower in women with overweight and obesity compared to women with normal BMI (P<0.05); but, the percentages of good blastocysts were similar in all studied patients. PRs, IRs and LBRs were significantly lower in the group of women with overweight and obesity compared to those women with normal weight (P<0.05). Obesity women had significantly more miscarriages compared to the others evaluated groups (P<0.05). Conclusion: Our data shows that an increased BMI affects the embryo development and significantly reduce the pregnancy, implantation and live birth rates.