Raquel Meirelles Gaspar Coelho Guimarães, Larissa Maciel Ribeiro, Lizandra Paravidine Sasaki, Hitomi Miura Nakagawa, Iris Oliveira Cabral
JBRA Assist. Reprod. 2021; 25 (3):500-507
Received August 13, 2020
Accepted January 15, 2021
Abstract
The oocyte quality could be negatively affected by many factors including smoking, alcohol consumption, obesity, woman´s age, endometriosis and controlled ovarian stimulation (COS), during the assisted reproductive technology (ART), in addition to genetic factors, such as hormone receptor polymorphisms, for example. It is known that the increase in the reactive oxygen specimens (ROS) due to systemic disorders causes biochemical and morphological changes in the oocytes, interfering with their quality. The oocyte dysmorphism can be expressed through intra and/or extra cytoplasmatic changes. In general, the size and number of oocytes morphological abnormalities are directly related to the preimplantation development failure. This case report is based on four in vitro fertilization (IVF) cycles performed by a patient in which oocyte dysmorphism was observed in all oocytes captured. The literature review on this topic aims to relate the characteristics of the oocytes, presented in the case report, with research results about the quality and morphology of the oocytes.
