Table 2. Controlled ovarian stimulation and laboratory outcomes for patients who received different protocols of gonadotropin-releasing hormone (GnRH) for pituitary suppression during controlled ovarian stimulation. LabRep–HC–UFG, 2012.
	Agonist	Antagonist	P
Ovarian stimulation
Days of rFSH (150 IU/day)	11.0 ± 1.77	9.24 ± 2.22	0.0091 a*
Total dose of rFSH required (IU) Pituitary downregulation	2094 ± 352.39	1365 ± 293.68	<0.0001 a*
Duration of suppression (days)	12 ± 1.63	3.60 ± 1.22	<0.0001 a*
Total dose of GnRH (mg) Clinical outcomes	1.2 ± 0.16	0.90 ± 0.30	0.0001 a*
Follicles ≥ 16 mm (rhCG day) Laboratory outcomes	6.76 ± 4.57	4.64 ± 3.21	0.04 a*
Oocytes retrieved	5.92 ± 4.58	4.16 ± 2.76	0.06 a
MII oocytes	4.48 ± 4.02	3.16 ± 2.21	0.27 a
2PN oocytes	2.20 ± 2.08	2.24 ± 2.31	0.91 a
Embryos cleaved	2.04 ± 2.0	2.16 ± 2.24	0.94 a
Embryos transferred (day 3) Fertilization rate	1.80 ± 1.29 40.1% (45/112)	1.72 ± 1.40 54.4% (43/79)	0.83 a 0.29 b
Implantation rate	13.3% (06/45)	9.3% (04/43)	0.42 b
Pregnancy per cycle	24% (06/25)	16% (04/25)	0.41 b
Miscarriages	10% (01/10)	20% (02/10)	0.53 b
a Mann-Whitney b x2 test MII – metaphase II 2PN – two pronucleus Values expressed as mean ± SD or % (number)