| Table 1. Parameters and ovarian stimulation outcomes according to AMH levels. | ||||||
| Parameter |
Group 1 AMH ≤ 0.30 |
Group 2 > 0.30 AMH ≤ 0.70 |
Group 3 > 0.70 AMH ≤ 1.0 |
Group 4 > 1.0 AMH < 3.0 |
Group 5 AMH ≥ 3.0 |
P-value |
|
Started cycles (287 total) |
64 | 76 | 32 | 86 | 29 | |
| BMI (kg/m2) |
22.95 ± 2.77 |
23.95 ± 3.84 |
23.79 ± 3.41 |
23.23 ± 3.71 |
24.08 ± 3.97 |
NS |
| Age |
37.83 ± 4.11a |
38.61 ± 3.67b |
38.15 ± 3.04c |
37.23 ± 3.64 |
35.48 ± 3.97abc |
abc<0.05 |
| Serum FSH |
12.45 ± 8.24abcd |
8.95 ± 5.54a |
7.99 ± 3.86b |
7.40 ± 3.11c |
6.81 ± 2.11d |
ab<0.01 cd<0.001 |
| AFC |
6.75 ± 3.47ab |
9.11 ± 4.93cde |
9.53 ± 3.74f |
12.60 ± 5.24acg |
17.58 ± 7.64bdefg |
abcefg<0.001 |
| Stimulation days |
9.59 ± 1.73 |
9.41 ± 1.74 |
10.03 ± 1.53 |
9.24 ± 1.50 |
8.93 ± 1.10 |
NS |
|
FSH administered (IU) |
1673.66 ± 538.88 |
1744.57 ± 707.02 |
1805.64 ± 562.79 |
1725.72 ± 623.76 |
1620.27 ± 559.93 |
NS |
|
Fol. ≥ 15 mm on hCG day |
3.64 ± 2.26abc |
5.36 ± 3.64de |
6.34 ± 3.98adf |
7.37 ± 3.60beg |
11.13 ± 4.22cfg |
bcefg<0.001 ad0.01 |
|
No. of oocytes retrieved |
3.27 ± 3.14abc |
6.23 ± 6.85ade |
5.87 ± 3.89fg |
9.25 ± 5.10bdfh |
16.96 ± 7.21cegh |
af<0.05 d<0.01 bcegh<0.001 |
| No. of metaphase II oocytes |
1.89 ± 2.15abc |
4.34 ± 5.96ad |
4.09 ± 3.12e |
6.30 ± 4.40bf |
11.44 ± 6.35cdef |
a<0.05 bcdef<0.001 |
|
Data are presented as mean values (± standard deviation); AMH: Anti-Müllerian hormone (ng/mL); FSH: Follicle Stimulating hormone; AFC: Antral Follicle Count; BMI: Body Mass Index; hCG: human Chorionic Gonadotropin. |
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