Table 1. Single medium versus sequential medium. Ongoing pregnancy rate outcomes. Random effects.
Trial Single-ECM n/N Sequential-ECM n/N RR 95%CI
Cleavage stage
Campo et al., 2010 18/85 19/87 0.97 0.55-1.70
Blastocyst stage
Sepulveda et al., 2009 28/40 20/40 1.40 0.98-2.07
Macklon et al., 2002 20/98 10/48 0.98 0.51-1.94
Cleavage and Blastocyst stages
Sfontouris et al., 2015 22/50 24/50 0.92 0.60-1.40
Total (Random effects) combined 88/273 73/225 1.11 0.87-1.40
Blastocyst stage only (Random effects) combined 48/138 30/88 1.29 0.93-1.78
    Total
Chi2=0.71      p=0.39
Cochran Q=2.72    p=0.44
I2=0% (95% CI=0% to 67.9%)
  Blastocyst stage only
Chi2=2.35      p=0.13
Cochran Q=0.90    p=0.34