Figure 2. Effects of nicotine on ovarian histology in pregnant Wistar rats. Mag: X400. H&E Staining technique A: Photomicrograph of an ovary section of control group stained with Haematoxylin and Eosin showing normal ovarian stroma (Slender arrow). There are some follicles with normal differential stages of maturation consisting majorly of graffian follicles (White arrow). There are normal theca cells (Blue arrow) seen and no vascular congestion B: Photomicrograph of an ovary section of nicotine treatment group stained with Haematoxylin and Eosin showing normal ovarian stroma with luteinization within the granular cells. There are some follicles with differential stages of maturation consisting of premordial and antral follicles (white arrow). There are normal theca cells (blue arrow) seen. There are severe vascular congestion seen and the stroma shows mild infiltration of inflammatory cells (Slender arrow)