Table 7. Effects of oral administration of Plukenetia conophora and 4H-Pyran-4-One 2,3-Dihydro-3,5-Dihydroxy-6-Methyl on malondialdehyde and nitric oxide levels of male Wistar rats treated with a single IP dose of 2 mg/kg of cadmium chloride
Group Testis Epididymis
MDA NO MDA NO
Control 4.36±0.98 2.50±0.33 4.91±1.38 3.13±0.16
Cadmium chloride 29.37±3.58+ 4.04±0.62+ 18.91±2.52+ 3.92±0.02
Cd+Vit E 9.24±0.70** 2.79±0.00* 6.74±0.22** 3.00±0.17*
Cd+100 mg/kg PC 6.41±0.88** 2.42±0.07* 6.06±0.68** 3.07±0.56
Cd+200mg/kg PC 5.34±1.32** 2.43±0.09* 4.51±0.15** 2.66±0.22*
Cd+25 mg/kg DDMP 10.93±1.82** 2.07±0.07* 9.51±1.63** 3.20±0.28
Cd+50 mg/kg DDMP 4.63±1.12** 2.83±0.24* 2.47±0.16** 3.11±0.00
Values are represented in mean values±SEM, n=6
+ p<0.05 when compared with controls
* p<0.05 when compared with the group given cadmium chloride alone
** p<0.01 when compared with the group given cadmium chloride aloneMDA - Malondialdehyde
NO - Nitric oxide
PC - Plukenetia conophora
DDMP - 4H-Pyran-4-One 2,3-Dihydro-3,5-Dihydroxy-6-Methyl