Table 8. Effects of oral administration of Plukenetia conophora and 4H-Pyran-4-One 2,3-Dihydro-3,5-Dihydroxy-6-Methyl on the testicular antioxidant status of male Wistar rats treated with a single IP dose of 2 mg/kg of cadmium chloride
Group SOD (U/ml) CAT (nmol/min/ml) GPX (nmol/min/ml) GST (nmol/min/ml)
Control 60.46±11.0 2.40±0.59 1.03±0.07 0.43±0.19
Cadmium chloride 9.68±4.10+ 0.89±0.13+ 0.78±0.01 0.07±0.02+
Cd+Vit E 68.00±5.20** 1.41±0.14 1.21±0.24 0.26±0.02*
Cd+100 mg/kg PC 61.85±12.80** 1.91±0.40 1.56±0.28* 0.36±0.13*
Cd+200mg/kg PC 66.62±4.60** 2.31±0.48* 1.69±0.26* 0.25±0.07*
Cd+25 mg/kg DDMP 57.93±9.65** 1.94±0.40* 1.50±0.11* 0.16±0.02
Cd+50 mg/kg DDMP 66.62±4.60** 2.65±0.40* 1.94±0.26* 0.32±0.08*
Values are represented in mean values±SEM, n=6
+ when compared with controls,
* p<0.05 when compared with the group given cadmium chloride alone
** p<0.01 when compared with the group given cadmium chloride aloneSuperoxide dismutase (SOD)
Catalase (CAT)
Glutathione peroxidase (GPX),
Glutathione-S-Transferase (GST)
PC - Plukenetia conophora
DDMP - 4H-Pyran-4-One 2,3-Dihydro-3,5-Dihydroxy-6-Methyl