Table 9. Effects of oral administration of Plukenetia conophora and 4H-Pyran-4-One 2,3-Dihydro-3,5-Dihydroxy-6-Methyl on the epididymal antioxidant status of male Wistar rats treated with a single IP dose of 2 mg/kg of cadmium chloride
Group SOD (U/ml) CAT (nmol/min/ml) GPX (nmol/min/ml) GST (nmol/min/ml)
Control 43.31±4.99 2.02±0.09 2.46±0.49 0.35±0.17
Cadmium chloride 13.89±2.39+ 0.74±0.13+ 0.96±0.06+ 0.08±0.03+
Cd+Vit E 30.09±2.71* 1.48±0.33* 1.07±0.07 0.19±0.02
Cd+100 mg/kg PC 30.88±5.19* 1.63±0.18* 1.31±0.21* 0.21±0.13*
Cd+200mg/kg PC 30.88±3.17* 2.07±0.06* 1.00±0.13* 0.18±0.02
Cd+25 mg/kg DDMP 36.29±3.44* 1.97±0.15* 1.62±0.24* 0.27±0.04*
Cd+50 mg/kg DDMP 35.13±3.94* 2.16±0.08* 1.49±0.31* 0.24±0.06*
Values are represented in mean values±SEM, n=6
+ p<0.05 when compared with controls,
* p<0.05 when compared with the group given cadmium chloride aloneSuperoxide dismutase (SOD)
Catalase (CAT)
Glutathione peroxidase (GPX)
Glutathione-S-Transferase (GST)
PC - Plukenetia conophora
DDMP - 4H-Pyran-4-One 2,3-Dihydro-3,5-Dihydroxy-6-Methyl