Table 1. Morphokinetic parameters and morphological events included in the time-lapse annotation. The parameters to be annotated were predetermined and agreed upon before the study onset. The parameters are based on recommendations from Ciray et al. (2014)
Parameter	Definition	Data collected
tPNa	Time at which pronuclei formation can be first identified	Time point
tPNf	Time at which both pronuclei have faded	Time point
tN	Time from insemination to completion of division of n cells	Time point
tM	Time from insemination to formation of a morula, where all cells have compacted and cell membranes are unclear	Time point
tSB	Time from insemination to start of blastulation, when the first sign of a cavity formation between two cells is visibly	Time point
tB	Time from insemination to formation of a full blastocyst, when the blastocoele cavity fills the embryo with less than 10% increase in its diameter	Time point
tEB	Time from insemination to expanded blastocyst, when the blastocyst has increased in diameter with more than 30% and the zona pellucida has started to thin	Time point
Even-ness	Even blastomeres at the two-cell stage, less than 20 % difference in size. Preferably at the time when both nuclei are visible	Binary; yes/no
Multinucleation	Presence of more than one nuclei in one or more blastomeres at the four cell stage	Binary; yes/no