Table 4. Mean annotated time points, expressed as hours post insemination (HPI), for all annotated embryos and for each insemination method. IVF embryos displayed significantly slower kinetics compared to ICSI embryos up until t8
Parameter	Mean time (HPI) n = 99	ICSI (HPI) n = 50	IVF (HPI) n=49	A IVF-ICSI (HPI)	p-value
tPB2	3.8±1.2	3.7±1.4	-	-	-
tPNa	7.5±1.9	7.5±1.1	7.9±1.0	+ 0.4	n.s.
tPNf	23.1±2.6	22.5±2.0	23.6±2.4	+ 1.0	<0.05
t2	25.6±2.6	25.1±2.7	26.1±2.5	+ 1.1	<0.05
t3	36.5±3.7	35.9±2.6	37.2±3.2	+ 1.4	<0.05
t4	37.4±3.6	36.7±4.0	38.1±3.6	+ 1.5	<0.05
t5	49.5±5.2	48.6±5.0	50.3±5.2	+ 1.7	<0.05
t6	51.1±5.2	50.3±3.3	51.9±4.8	+ 1.7	<0.05
t7	53.0±6.2	51.9±5.1	54.1±6.1	+ 2.2	<0.05
t8	56.3±9.1	54.7±6.2	57.8±9.0	+ 3.1	<0.05
t9 +	71.8±7.4	70.4±8.9	73.1±6.7	+ 2.7	n.s.
tM	86.5±7.4	86.0±6.9	87.0±9.5	+ 1.0	n.s.
tSB	98.6±6.7	98.4±7.0	98.7±6.6	+ 0.3	n.s.
tB	106.6±6.2	106.7±6.8	106.4±5.9	- 0.2	n.s.
tEB	111.2±5.2	111.0±6.6	111.4±4.9	+ 0.4	n.s.