Table 2. Effect of aqueous extract of Senecio biafrae leaves on the sperm profile of adult male Sprague Dawley rats with tetracycline-induced infertility after 28 days of administration
Parameters Groups
A B C D E F
Sperm court (x 106/ml) 79.65±2.50 33.03±2.34β 67.38±3.59β 87.19±2.03¥ 89.45±4.15α 72.35 ± 2.32¥
Sperm motility (%) 67.09±3.80 34.45±2.36β 68.95±3.40 83.72±2.45α,¥ 90.12± 3.12α 63.11 ±3.21¥
Progressivity X0 Y0 X0 X0 X0 X0
Normal morphology(%) 74.86±1.98 32.34±2.43β 75.11±3.10 85.68±2.06¥ 87.34±6.23α,¥ 68.45± 5.13¥
Abnormal morphology(%) 22.56±2.07 68.50±2.01α 22.31±2.44 14.61±1.39β,¥ 12.57±2.32β,¥ 25.43±3.12¥
Sperm live /dead ratio (%) 76.45±2.03 28.75±1.28β 77.46±3.71 87.47±2.42¥ 89.35±4.12α,¥ 69.21±5.23α,¥
Values are expressed as Mean ± S.E.M, n=6 in each group
α: significantly greater than control group
β: significantly lower than control group
¥: significantly different from group C at p<0.05. One-Way ANOVA.
X0: Rapid linear progressive motility
Y0: Slow linear progressive motility
A: (Control) 2ml/kg of body weight of normal saline
B: 30 mg/kg of body weight of Tetracycline
C: 30 mg/kg of body weight of Tetracycline and 50 mg/kg of body weight of vitamin C
D: 30 mg/kg of body weight of Tetracycline and 500 mg/kg of body weight of Senecio biafrae extract
E: 30mg/kg of body weight of Tetracycline + 50 mg/kg of body weight of vitamin C + 500 mg/kg body weight of Senecio biafrae extract
F: 30 mg/kg of body weight of Tetracycline reversal