| Table 2. Effect of aqueous extract of Senecio biafrae leaves on the sperm profile of adult male Sprague Dawley rats with tetracycline-induced infertility after 28 days of administration | ||||||
| Parameters | Groups | |||||
|---|---|---|---|---|---|---|
| A | B | C | D | E | F | |
| Sperm court (x 106/ml) | 79.65±2.50 | 33.03±2.34β | 67.38±3.59β | 87.19±2.03¥ | 89.45±4.15α | 72.35 ± 2.32¥ |
| Sperm motility (%) | 67.09±3.80 | 34.45±2.36β | 68.95±3.40 | 83.72±2.45α,¥ | 90.12± 3.12α | 63.11 ±3.21¥ |
| Progressivity | X0 | Y0 | X0 | X0 | X0 | X0 |
| Normal morphology(%) | 74.86±1.98 | 32.34±2.43β | 75.11±3.10 | 85.68±2.06¥ | 87.34±6.23α,¥ | 68.45± 5.13¥ |
| Abnormal morphology(%) | 22.56±2.07 | 68.50±2.01α | 22.31±2.44 | 14.61±1.39β,¥ | 12.57±2.32β,¥ | 25.43±3.12¥ |
| Sperm live /dead ratio (%) | 76.45±2.03 | 28.75±1.28β | 77.46±3.71 | 87.47±2.42¥ | 89.35±4.12α,¥ | 69.21±5.23α,¥ |
| Values are expressed as Mean ± S.E.M, n=6 in each group α: significantly greater than control group β: significantly lower than control group ¥: significantly different from group C at p<0.05. One-Way ANOVA. X0: Rapid linear progressive motility Y0: Slow linear progressive motility A: (Control) 2ml/kg of body weight of normal saline B: 30 mg/kg of body weight of Tetracycline C: 30 mg/kg of body weight of Tetracycline and 50 mg/kg of body weight of vitamin C D: 30 mg/kg of body weight of Tetracycline and 500 mg/kg of body weight of Senecio biafrae extract E: 30mg/kg of body weight of Tetracycline + 50 mg/kg of body weight of vitamin C + 500 mg/kg body weight of Senecio biafrae extract F: 30 mg/kg of body weight of Tetracycline reversal |
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