| Table 3. Effect of aqueous extract of Senecio biafrae leaves on the hormone profile of adult male Sprague Dawley rats with tetracycline-induced infertility after 28 days of administration | ||||||
| Parameters | Groups | |||||
|---|---|---|---|---|---|---|
| A | B | C | D | E | F | |
| TT (ng/ml) | 1.94±0.14 | 0.83±0.14β | 1.67±0.11** | 1.81±0.08** | 1.92±0.06** | 1.81±0.12** |
| FSH (mlU) | 0.24±0.02 | 0.15±0.01β | 0.24±0.02** | 0.29±0.02** | 0.30± 0.01** | 0.21±0.02** |
| LH (mlU) | 0.18±0.01 | 0.11±0.01β | 0.19±0.01** | 0.21±0.02** | 0.25±0.04** | 0.16±0.02** |
| Values are expressed as Mean ± S.E.M, n=6 in each group **: significantly dissimilar from group B β: significantly lower than control group, at p<0.05. One-Way ANOVA. TT: testosterone, FSH: follicle stimulating hormone, LH: leutenizing hormone, A: (Control) 2 ml/kg of body weight of normal saline B: 30 mg/kg of body weight of Tetracycline C: 30 mg/kg of body weight of Tetracycline and 50 mg/kg of body weight of vitamin C D: 30 mg/kg of body weight of Tetracycline and 500 mg/kg of body weight of Senecio biafrae extract E: 30 mg/kg of body weight of Tetracycline + 50mg/kg of body weight of vitamin C + 500 mg/kg body weight of Senecio biafrae extract F: 30mg/kg of body weight of Tetracycline reversal |
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