Table 3. Effect of aqueous extract of Senecio biafrae leaves on the hormone profile of adult male Sprague Dawley rats with tetracycline-induced infertility after 28 days of administration
Parameters Groups
A B C D E F
TT (ng/ml) 1.94±0.14 0.83±0.14β 1.67±0.11** 1.81±0.08** 1.92±0.06** 1.81±0.12**
FSH (mlU) 0.24±0.02 0.15±0.01β 0.24±0.02** 0.29±0.02** 0.30± 0.01** 0.21±0.02**
LH (mlU) 0.18±0.01 0.11±0.01β 0.19±0.01** 0.21±0.02** 0.25±0.04** 0.16±0.02**
Values are expressed as Mean ± S.E.M, n=6 in each group
**: significantly dissimilar from group B
β: significantly lower than control group, at p<0.05. One-Way ANOVA.
TT: testosterone, FSH: follicle stimulating hormone, LH: leutenizing hormone,
A: (Control) 2 ml/kg of body weight of normal saline
B: 30 mg/kg of body weight of Tetracycline
C: 30 mg/kg of body weight of Tetracycline and 50 mg/kg of body weight of vitamin C
D: 30 mg/kg of body weight of Tetracycline and 500 mg/kg of body weight of Senecio biafrae extract
E: 30 mg/kg of body weight of Tetracycline + 50mg/kg of body weight of vitamin C + 500 mg/kg body weight of Senecio biafrae extract
F: 30mg/kg of body weight of Tetracycline reversal