Table 3. Blood levels of some hematological indices in Sprague-Dawley rats following 28 days oral administration of Solanum nigrum
Parameters Groups
A (2 ml/kg) control B (100 mg/kg) C (300 mg/ kg) D (500 mg/kg)
PCV (%) 70.64±0.80 72.55±0.60 80.49±1.41* 89.34±1.78*
Hb (g/dl) 66.52±1.02 74.68±1.54* 62.77±0.57** 71.65±1.37*
WBC Count (X106mL-1) 9.01±0.29 13.80±0.43* 18.28±0.45* 24.72±0.37*
RBC Count (106/mm3) 10.57±0.25 11.41±0.17 14.62±0.27* 17.82±0.46*
Values are expressed as Mean ± S.E.M
n=10 in each group
* Represent significant increased from the control group at p<0.05
** represent significant decreased from the control.
One-Way ANOVA.
PCV: Packed cell volume Red Blood Cell Counts (RBC), White Blood Cell Counts (WBC),
Hemoglobin Concentration (Hb),
A: 2ml/kg b.wt of normal saline
B: 100 mg/kg b.wt of Solanum nigrum extract
C: 300 mg/kg b.wt of Solanum nigrum extract.
D: 500 mg/kg b.wt of Solanum nigrum extract