
Figure 2. Effect of clomid on testicular histology and androgen receptor (AR) expression in male Wistar rats exposed to lead acetate (A): Control group showed moderate AR expression (white arrow), normal seminiferous tubules with the presence of spermatozoa strand in the lumen (black arrow) and normal stratification of germ cell layer (spanned). (B): Clomid group showed strong AR expression (white arrow), normal seminiferous tubules and stratification of spermatogenic cells (spanned) with the presence of whorl spermatozoa (black arrow). (C): Pb group showed mild AR expression (white arrow), widened interstitial space and lumen (black arrow) were observed with sloughing and arrest of germ cell layer stratification (spanned). (D): Clomid + Pb group showed moderate AR expression (white arrow), some normal germ cell layers (spanned) with a moderate lumen (black arrow) and normal seminiferous tubules.