| Supplementary Table I. List of proteins identified exclusively in the FF from PCOS group in comparison to OD group | |||||
| SwissProt ID | Name | Class | Molecular Function | Cellular compartment | Number of Patients |
| Q17R60 | Interphotoreceptor matrix proteoglycan 1 | Glicoproteína de matriz extracelular (PC00102); receptor (PC00100) | receptor activity (GO:0004872) | extracellular region(GO:0005576) | 3 |
| Q8WXI7 | Mucin-16 | NA | NA | NA | 3 |
| PNA1NA42 | Complement C3 | NA | cysteine-type endopeptidase inhibitor activity (GO:0003824) | #N/D | 2 |
| P02765 | Alpha-2-HS- glycoprotein | Inibidor de cisteína protease (PC00095); Glicoproteína de matriz extracelular (PC00191) | peptidase inhibitor activity (GO:0003824) | extracellular space(GO:0005576) | 2 |
| P02774 | Vitamin D-binding protein | NA | NA | NA | 2 |
| Q15020 | Squamous cell carcinoma antigen recognized by T-cells 3 | NA | NA | NA | 2 |
| A6NDX4 | Putative transmembrane protein | NA | NA | #N/D | 1 |
| O14526 | FCH domain only protein 1 | Proteína de citoesqueleto da família das actinas (PC00085); proteína reguladora detrafficking de membrana (PC00041) | NA | NA | 1 |
| O14578 | Citron Rho-interacting kinase | non-receptor serine/threonine protein kinase(PC00220) | protein kinase activity (GO:0003824) | NA | 1 |
| O15020 | Spectrin beta chain, non-erythrocytic 2 | non-motor actin binding protein (PC00085) | actin binding (GO:0005488); structural constituent of cytoskeleton (GO:0005515) | intracellular (GO:0044464) | 1 |
| O15357 | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 | phosphatase (PC00121) | NA | NA | 1 |
| O75445 | Usherin | extracellular matrix linker protein (PC00102); receptor (PC00101) | receptor activity (GO:0004872) | extracellular matrix(GO:0031012); extracellular region(GO:0005576) | 1 |
| O75691 | Small subunit processome component 20 homolog | NA | NA | intracellular (GO:0044464); nucleolus (GO:0005622); ribonucleoprotein complex(GO:0043226) | 1 |
| P00739 | Haptoglobin-related protein | annexin (PC00060); calmodulin (PC00050); peptide hormone (PC00131); protease inhibitor (PC00061); receptor (PC00207); serine protease (PC00179) | NA | NA | 1 |
| P01008 | Antithrombin-III | serine protease inhibitor (PC00095) | serine-type endopeptidase inhibitor activity (GO:0003824); serine-type peptidase activity(GO:0016787) | extracellular space(GO:0005576) | 1 |
| P01019 | Angiotensinogen | serine protease inhibitor (PC00095) | serine-type endopeptidase inhibitor activity (GO:0003824); serine-type peptidase activity(GO:0016787) | extracellular space(GO:0005576) | 1 |
| P02538 | Keratin, type II cytoskeletal 6A | intermediate filament (PC00085); structural protein (PC00129) | structural constituent of cytoskeleton (GO:0005198) | intermediate filament cytos keleton (GO:0043226); intracellular (GO:0005856) | 1 |
| P02671 | Fibrinogen alpha chain | signaling molecule (PC00207) | receptor binding(GO:0005488) | extracellular region(GO:0005576) | 1 |
| P02675 | Fibrinogen beta chain | signaling molecule (PC00207) | receptor binding (GO:0005488) | extracellular region(GO:0005576) | 1 |
| P02679 | Fibrinogen gamma chain | NA | NA | NA | 1 |
| P02790 | Hemopexin | transfer/carrier protein (PC00219) | NA | extracellular matrix(GO:0031012) | 1 |
| P04259 | Keratin, type II cytoskeletal 6B | intermediate filament (PC00085) structural protein (PC00129) | structural constituent of cytoskeleton (GO:0005198) | intermediate filament cytoskeleton (GO:0043226); intracellular (GO:0005856) | 1 |
| P08574 | Cytochrome c1, heme protein, mitochondrial | NA | NA | cytoplasm (GO:0044464); mitochondrion (GO:0005622) | |
| P08603 | Complement factor H | NA | NA | NA | 1 |
| P09529 | Inhibin beta B chain | growth factor(PC00207) | transforming growth factor beta receptor binding(GO:0005488) | extracellular space(GO:0005576) | 1 |
| P13645 | Keratin, type I cytoskeletal 10 | intermediate filament (PC00085); tructural protein (PC00129) | structural constituent of cytoskeleton (GO:0005198) | intermediate filament cytoskeleton (GO:0043226); intracellular (GO:0005856) | 1 |
| P19827 | Inter-alpha-trypsin inhibitor heavy chain H1 | serine protease inhibitor (PC00095) | protein binding (GO:0005488); serine-type endopeptidase inhibito activity (GO:0005515) | NA | 1 |
| P20742 | Pregnancy zone protein | complement component (PC00090); ytokine (PC00078); serine protease inhibitor (PC00207) | cytokine activity (GO:0005488); serine-type endopeptidase inhibitor activity(GO:0005515) | NA | 1 |
| P27169 | Serum paraoxonase/arylesterase 1 | NA | hydrolase activity, acting on ester bonds (GO:0003824) | NA | 1 |
| P33991 | DNA replication licensing factor MCM4 | DNA helicase (PC00171); hydrolase (PC00009) | DNA helicase activity (GO:0003824); hydrolase activity (GO:0004386); nucleic acid binding(GO:0003678) | NA | 1 |
| P35908 | Keratin, type II cytoskeletal 2 epidermal | intermediate filament (PC00085); structural protein (PC00129) | structural constituent of cytoskeleton (GO:0005198) | intermediate filament cytoskeleton (GO:0043226); intracellular (GO:0005856) | 1 |
| P48668 | Keratin, type II cytoskeletal 6C | intermediate filament (PC00085); tructural protein (PC00129) | structural constituent of cytoskeleton (GO:0005198) | intermediate filament cytoskeleton (GO:0043226); intracellular (GO:0005856) | 1 |
| P49454 | Centromere protein F | NA | NA | NA | 1 |
| P49589 | Cysteine--tRNA ligase, cytoplasmic | RNA binding protein (PC00171); aminoacyl-tRNA synthetase (PC00031) | aminoacyl-tRNA ligase activity(GO:0003824) | cytosol(GO:0044464) | 1 |
| P49842 | Serine/threonine-protein kinase 19 | NA | NA | NA | 1 |
| P78312 | Protein FAM193A | NA | NA | NA | 1 |
| P98170 | E3 ubiquitin-protein ligase XIAP | protease inhibitor (PC00095) | cysteine-type endopeptidase inhibitor activity (GO:0003824); ubiquitin-protein ligase activity(GO:0016787) | cytoplasm (GO:0044464); microtubule (GO:0005622); nucleus (GO:0005737) | 1 |
| Q12873 | Chromodomain- helicase-DNA- binding protein 3 | DNA helicase (PC00171) | NA | NA | 1 |
| Q13129 | Zinc finger protein Rlf | nuclease (PC00171); transcription factor (PC00170) | nuclease activity (GO:0003824); sequence-specific DNA binding transcription factor activity (GO:0016787) | NA | 1 |
| Q15813 | Tubulin-specific chaperone E | chaperone (PC00072) | NA | NA | 1 |
| Q3KP22 | Uncharacterized protein C11orf85 | NA | NA | NA | 1 |
| Q53GS7 | Nucleoporin GLE1 | nucleic acid binding (PC00171); transfer/carrier protein (PC00219) | nucleic acid binding (GO:0005488) | NA | 1 |
| Q63HN8 | E3 ubiquitin-protein ligase RNF213 | NA | NA | NA | 1 |
| Q6YP21 | Kynurenine-- oxoglutarate transaminase 3 | transaminase (PC00220) | transaminase activity (GO:0003824) | NA | 1 |
| Q70CQ2 | Ubiquitin carboxyl-terminal hydrolase 34 | NA | NA | NA | 1 |
| Q7Z6M1 | Rab9 effector protein with kelch motifs | NA | NA | NA | 1 |
| Q86YQ8 | Copine-8 | membrane traffic protein (PC00150) | NA | NA | 1 |
| Q8IWT3 | Cullin-9 | NA | NA | NA | 1 |
| Q8IY50 | Putative thiamine transporter SLC35F3 | NA | NA | NA | 1 |
| Q8N9W7 | Putative transmembrane protein FLJ36131 | NA | #N/D | #N/D | 1 |
| Q8NHM4 | Putative trypsin-6 | serine protease (PC00121) | serine-type peptidase activity(GO:0003824) | extracellular space(GO:0005576) | 1 |
| Q8TDI0 | Chromodomain- helicase-DNA-binding protein 5 | DNA helicase (PC00171) | NA | NA | 1 |
| Q8TF01 | Arginine/serine-rich protein PNISR | NA | NA | NA | 1 |
| Q92665 | 28S ribosomal protein S31, mitochondrial | NA | NA | NA | 1 |
| Q9H1H9 | Kinesin-like protein KIF13A | microtubule binding motor protein (PC00085) | microtubule motor activity(GO:0003824) | cytoskeleton (GO:0043226); intracellular (GO:0005856); protein complex (GO:0044464) | 1 |
| Q9NQ66 | 1-phosphatidy linositol4,5- bisphosphate phosphodiesterase beta-1 | calcium- binding protein (PC00060); guanyl- nucleotide exchange factor (PC00095); phospholipase (PC00022); signaling molecule (PC00113) | calcium ion binding (GO:0005488); guanyl-nucleotide exchange factor activity (GO:0005509); hospholipase activity (GO:0003824); receptor binding (GO:0030234); small GTPase regulator activity (GO:0005085) | NA | 1 |
| Q9NTG1 | Polycystic kidney disease and receptor for egg jelly-related protein | G-protein modulator (PC00095); ion channel (PC00022); membrane -bound signaling molecule (PC00227) | Cation channel activity (GO:0005215) | NA | 1 |
| Q9P212 | 1-phosphatidy linositol 4,5- bisphosphate phosphodiesterase epsilon-1 | calcium- binding protein (PC00060); guanyl- nucleotide exchange factor (PC00095); phospholipase (PC00022); signaling molecule (PC00113) | calcium ion binding (GO:0005488); guanyl-nucleotide exchange factor activity (GO:0005509); phospholipase activity (GO:0003824); receptor binding (GO:0030234); small GTPase regulator activity (GO:0005085) | NA | 1 |
| Q9P225 | Dynein heavy chain 2, axonemal | hydrolase (PC00121); microtubule binding motor protein (PC00085) | microtubule motor activity (GO:0003824); structural constituent of cytoskeleton (GO:0016787) | intracellular (GO:0044464); microtubule (GO:0005622) | 1 |
| Q9P2N5 | RNA-binding protein 27 | RNA binding protein (PC00171) | RNA binding (GO:0005488) | NA | 1 |
| Q9UKA4 | RNA-binding protein 27 | kinase modulator (PC00095) | protein binding (GO:0005488) | cytoplasm (GO:0044464) | 1 |