Table 1. Main genes associated with male infertility
Gene	Disease	Clinical aspects
CFTR	congenital bilateral absence of the vas deferens	Obstructive azoospermia
KAL-1	Kallmann syndrome	Hypogonadotropic hypogonadism and changes in spermatogenesis
AR	Androgen insensitivity syndrome	Decreased androgen sensitivity and changes in spermatogenesis
INSL3-RXFP2	Cryptorchidism	Changes in spermatogenesis
Source: Asero et al., 2014.