| Table 2. ICSI cycle characteristics of the different age groups. | |||||
| Group A |
Group B |
Group C |
Group D |
p>-value | |
|---|---|---|---|---|---|
| Baseline FSH (IU/L) | 14.6±5.3 | 14.1±4.3 | 14.1±4.3 | 16.0±5.8b | <0.01Ω |
|
FSH level I (%)
|
71.1 |
71.7 |
60.4 |
56.9 |
<0.01¥ |
| Baseline LH (IU/L) | 6.5±2.8 | 6.5±3.4 | 6.7±3.6 | 6.6±2.8 | 0.9£ |
| Gonadotropin dose (IU) | 2196±742 | 2257±773 | 2555±844ab | 2496±911ab | 0.05Ω |
| Peak E2 level (pg/mL) | 1000±884 | 764±560a | 654±542a | 556 ± 476ab | <0.01£ |
| No. of oocytes | 6.0±5.1 | 4.5±3.4a | 3.4±3.1ab | 2.5±2ab | 0.01Ω |
| Poor response (%) (0-3 oocytes) | 37.8 | 46.4 | 62.3ab | 73.3abc | 0.001¥ |
| No. of mII oocytes | 4.2±4 | 3.3±2.6a | 2.5±2.4ab | 1.9±1.6ab | 0.01£ |
| Fertilization rate (%) | 71.7±32.4 | 75.2±29.1 | 75±32.5 | 75.9±34.1 | 0.9¥ |
| No. of embryos | 3.5 ± 3.3 | 2.8 ± 2.3a | 2.1 ± 2.2ab | 1.5±1.4abc | 0.01£ |
| No. of embryos transferred | 1.1±0.3 | 1.2±0.4a | 1.5±0.5ab | 1.4±0.5ab | 0.01Ω |
| Embryo transfer/opu (%) | 83.9 | 86.9 | 79.4b | 70.7abc | 0.001¥ |
| Clinical pregnancy rate (%) | 23.9 (43/180) | 23.5 (79/336) | 18.2 (69/379) | 5.2(6/116)abc | 0.001¥ |
| Live birth rate (%) | 21.1 (38/180) | 19.3 (65/336) | 10.6 (40/379)ab | 1.7 (2/116)abc | 0.001¥ |
| Miscarriage/clinical preg (%, n) | 11.6 (5/43) | 17.7 (14/79) | 42.0 (29/69)ab | 66.7 (4/6)ab | 0.001¥ |
aDifferent from group A
bDifferent from group B
cDifferent from group C
ΩOne Way ANOVA
¥Chi Square Test
£Kruskal-Wallis Test
Pairwise Comparison with Bonferroni and Bonferroni-Dunn Test