Figure 5. A: Group A showing normal histoarchitecture with typically organized layers of spermatogenic cells at different stages of maturation (Yellow arrow), no pathological changes in the lumen (L) of the seminiferous tubules, spermatozoa (SP), basement membrane (blue arrow) and interstitial space (I); B: Group B showing testicular photomicrograph section of Arsenic-only group showing distortion of the tubular architecture and disorganization of the spermatogenic cells (yellow arrow) in seminiferous tubules, hypocellularity due to degeneration of germ cells, disruption of spermatogenesis and vacuolation (*) and empty lumen (L); C: Group C showing a testicular photomicrograph section of arsenic and DRLC treated group at low dose, showing restored lumen (L) with visible spermatozoa (SP), abundant sperm cells (yellow arrow); D: Group D showing testicular photomicrograph section of arsenic and DRLC treated group at high dose, showing a notable restoration of the lumen (L) of the seminiferous tubules, with visible spermatozoa (SP) and abundant sperm cell (yellow arrow) Stains: Hematoxylin and Eosin. Mg X400.