Figure 3. Comparative characteristic of PR-A, PR-B and Ki67 mRNAs expression in leiomyoma tissue explants and leiomyoma primary cultures cells, incubated at different progesterone concentrations (P4) Real-time PCR shows the effect of progesterone on Ki67 (a), PR-A (b) PR-B (c) mRNAs expression in leiomyoma tissue explants and leiomyoma primary cultures cells. Results are presented as median, first quartiles, third quartiles. *- p<0.05, Mann-Whitney U-test with controls, x - p<0.05, Mann-Whitney U-test with explants.