Figure 10. Confocal microscopy images demonstrating mitochondria distribution during maturation of human oocytes. (A) GV oocyte displays the distribution of mitochondria in the peripheral zone. (B) GV oocyte with mitochondria diffused fairly in the cytoplasm. (C) MI oocyte with mitochondria displaying a peripheral type of distribution. (D) In vitro matured oocyte indicating the semiperipheral distribution of mitochondria in the oocyte. (E) In vitro matured oocyte showing the distribution of mitochondria throughout the cytoplasm. (F) In vivo matured oocyte: mitochondria are disseminated throughout the cytoplasm, and there are mitochondria in the central region. Scale bar represents 50 μm. Liu et al. (2010) with permission.