| Table 2. Descriptive analysis of patients’ demographics, response to COS and laboratorial ICSI outcomes in repeated cycles. | |||
| Variables | r-hCG Trigger (n=18) | Dual Trigger (n=18) | p-value |
| Female age (years) | 37.83±0.77 | 38.22±0.77 | 0.721 |
| Male age (years) | 39.06±0.93 | 39.44±0.93 | 0.767 |
| Female BMI | 24.66±0.58 | 25.33±0.58 | 0.414 |
| FSH dose (IU) | 2875.00±190.44 | 2625.00±201.99 | 0.368 |
| Length of stimulation (days) | 10.41±1.33 | 10.47±1.70 | 0.911 |
| Length of pituitary suppression (days) | 4.76±0.83 | 4.53±1.23 | 0.518 |
| Total number of follicles on trigger day | 11.17±1.799 | 10.56±1.80 | 0.810 |
| Mature follicular rate (%) | 46.63±20.30 | 34.54±21.23 | 0.095 |
| Estradiol level (pg/mL) | 1246.67±261.21 | 1431.22±301.62 | 0.644 |
| Number of retrieved oocytes | 7.17±1.36 | 7.72±1.36 | 0.772 |
| Oocyte yield (%) | 60.83±3.18 | 84.38±3.25 | <0.001 |
| MII oocyte rate (%) | 59.50±2.44 | 74.29±3.26 | <0.001 |
| MI oocyte rate (%) | 18.22±2.63 | 5.80±2.55 | <0.001 |
| PI oocyte rate (%) | 16.11±1.34 | 10.00 ± 0.95 | <0.001 |
| Fertilization rate (%) | 80.00±2.83 | 88.12±2.35 | 0.027 |
| Blastocyst development rate (%) | 18.21±1.14 | 41.67±2.63 | <0.001 |
Note: Retrospective case-control within-subject analysis performed to compare the response to COS and ICSI outcomes in patients who had the first ICSI cycle triggered with r-hCG only and the following ICSI cycle triggered with GnRH agonist and r-hCG. Values are mean ± standard error, unless otherwise noted. COS – controlled ovarian stimulation, ICSI – intracytoplasmic sperm injection, r-hCG – recombinant human chorionic gonadotropin.