| Table 1. Effect of Cleistanthus collinus on body weight, testicular weight and epididymal weight of Wistar rats. | ||||
| Control (saline) | Cyclophosphamide 100 mg/kg | C. collinus 200 mg/kg | C. collinus 400 mg/kg | |
|---|---|---|---|---|
| Change in body weight (g) | 52.16±13.22 | -59.16±7.49c | -39±9.12b | -51.66±12.86b |
| Testes (g) | 1.22 (1.01-1.25) | 0.79 (0.72-0.89)c | 0.95 (0.9-1.26)b | 0.89 (0.86-0.98)b |
| Epididymis (g) | 0.45±0.03 | 0.38±0.06a | 0.44±0.04 | 0.39±0.03 |
(-) Indicates reduction in body weight. Rats received saline or plant extract through oral gavage daily for 28 days. Cyclophosphamide was given through the intraperitoneal route once a week for four weeks. Data are represented as mean ± SD or median (IQR), n=6. ap<0.05, bp<0.01, cp<0.001 compared to the control group. The parametric test used was one way ANOVA with the Tukey Krammer post hoc test and the Non-parametric test used was the Kruskal Wallis with Dunn’s multiple comparison post hoc test, based on the normality testing.