| Table 2. Effect of Cleistanthus collinus on sperm count and testicular parameters of Wistar rats. | ||||
| Control (Saline) | Cyclophosphamide (100 mg/kg) | C. collinus (200 mg/kg) | C. collinus (400 mg/kg) | |
|---|---|---|---|---|
| Sperm count (x 106) | 51.52 (38.35-54.65) | 19.75 (18.0-42)c | 35.42 (33.65-47.0)d | 29.32 (28.65-47.5)b |
| Area of seminiferous tubules (mm2) | 584.83±16.01 | 374.50±46.68c | 385.83±67.88c | 356.0±47.19c |
| Johnson’s scoring | 9.40 (9-9.9) | 7.00 (0-8.1)b | 8.65 (8-9.4) | 7.30 (5.2-8.1)b |
Rats received saline or plant extract through oral gavage daily for 28 days. Cyclophosphamide was given through the intraperitoneal route once a week for four weeks. The following day, the animals were slaughtered, and the parameters were assessed. The data are represented as mean ± SD or median (IQR), n=6. ap< 0.05, bp<0.01, cp<0.001, compared with the control group. dp<0.05 compared with the cyclophosphamide group. The parametric test used was one way ANOVA with Tukey Krammer post hoc test and the Non-parametric test used was the Kruskal Wallis with Dunn’s multiple comparison post hoc test, based on the normality testing.